电子邮箱：quande_wang@163.com

       办公地址：国家重点实验室2号楼503

研究方向

    1. 自由基氟化学

    2. 含氟功能分子药物化学研究

教育背景

       2015.08 至 2019.11，香港中文大学化学系，博士，导师：Gavin Chit Tsui

       2009.09 至 2012.07，山东大学药学院，硕士，导师：方浩教授

       2005.09 至 2009.07， 山西医科大学药学院，本科

工作经历

       2019.12 至今，广西师范大学，化学与药学学院/省部共建药用资源化学与药物分子工程国家重点实验室

       2015.03 至 2015.07，云南白药集团创新研发中心

       2012.07 至 2014.11，药明康德新药开发有限公司

独立工作后论文发表情况：

1. Book chapter: Quande Wang*, Functions Containing Four Halogens or Three Halogens and One Other Heteroatom Substituent.In Comprehensive Organic Functional Group Transformations III (Gary A. Molander, Ed), Elsevier, in press.

2. Mingxi Chen, Jingjing Ling (本科生), Keguang Cheng*, Quande Wang*. Photocatalytic C-H Trifluoroethoxylation of (Hetero)arenes. Org. Lett. 2025, 27,  2241–2246

3.  Ning Chen, Jingjing Ling (本科生), Keguang Cheng, Hai-Tao Tang*, Quande Wang*. N-Monofluoromethoxy Benzoimidazole: A Bench Stable Reagent for Direct Radical Monofluoromethoxylation of Alkenes. Sci. China Chem. 2025, 68, https://doi.org/10.1007/s11426-024-2524-9.

4. Mingxi Chen, Yuhui Lu, Yiwen Shen, Quande Wang*. N-Trifluoroethoxy Benzotriazolium Triflate: A Readily Available Reagent for Direct Radical Trifluoroethoxylation of Alkenes. Org. Lett. 2024, 26, 9586-9591.

5. Shichao Tian, Ning Chen, Keguang Cheng*, Quande Wang*. Radical Acylfluoroalkylation of 1,3-Enynes via N-Heterocyclic Carbene/Photoredox Cooperative Catalysis. Org. Lett. 2024, 26, 4351-4355.

6. Mingxi Chen, Quande Wang*. Fluoroalkoxylating Reagents in Organic Synthesis: Recent Advances.  Eur. J. Org. Chem. 2024, e202400316 (Invited review).

7. Feng Liang, Ning Chen, Keguang Cheng,* and Quande Wang*. N-Heterocyclic Carbene and Manganese Synergistic Catalysis: A Three-Component Radical Acylmonofluoroalkylation of Alkenes. Org. Lett. 2023, 25, 8168−8172. 

8. Shichao Tian, Mingxi Chen, Yihan Tang, Keguang Cheng*, Gavin Chit Tsui*, Quande Wang*. Acylmonofluoromethylation of alkenes via dual NHC/photoredox catalysis. Org. Chem. Front. 2023, 10, 6124-6130. 

9. Yuqing Zhou, Shichao Tian, Lixin Shen, Liqiong Zhang, Jingjing Liu, Weibin Mo*, Quande Wang*, Keguang Cheng*. Design, synthesis and in vitro antitumor activity of 17β-estradiol-amino acid derivatives. Arab. J. Chem. 2024, 17, 105539.

10. Liqiong Zhang, Li Sun, Yuqing Zhou, Jingjing Liu, Quande Wang*, Weibin Mo*, Keguang Cheng*. Pentacyclic triterpene-amino acid derivatives induced apoptosis and autophagy in tumor cells, affected the JNK and PI3K/AKT/mTOR pathway. Bioorg. Med. Chem. 2023, 94, 117478. 

11. Shaoting Chen, Yuxiang Zheng, Benji Liang, Yudong Yin, Jian Yao, Quande Wang*, Yanghan Liu*, Nouri Neamati*. The application of PROTAC in HDAC. Eur. J. Med. Chem. 2023, 260, 115746. 

12. Yudong Yin, Li Sun, Lixin Sheng, Liqiong Zhang, Jingjing Liu, Xiaoan Wen, Weibin Mo, Quande Wang*, Keguang Cheng*. (4-Picolylamino)-17β-Estradiol derivative and analogues induce apoptosis with death receptor trail R2/DR5 in MCF-7. Chem-Bio. Interact. 2023, 369, 110286.

13. Kun She, Feng Liang, Shichao Tian, Hengshan Wang*, Gavin Chit Tsui*, Quande Wang*. Organocatalytic Three-Component Acyldifluoromethylation of Vinylarenes via N-Heterocyclic Carbene-Catalyzed Radical Relay. Org. Lett. 2022, 24, 4840−4844.