石伟
（生药学博士，副教授，硕士研究生导师）
联系方式：swv2012@163.com
地址：省部共建药用资源化学与药物分子工程国家重点实验室2号楼
个人简介
石伟，男，生药学博士（中国药科大学）。现为广西师范大学化学与药学学院教师，主要从事中药药效物质基础与质量控制研究，至今已获得国家自然科学基金地区基金、广西自然科学基金(青年基金，面上项目)、广西高校中青年教师科研基础能力提升项目、省部共建药用资源化学与药物分子工程国家重点实验室人才引进项目等项目资助。已在Journal of Ethnopharmacology、Frontiers in Pharmacology、Food and Chemical Toxicology、Chemical Research inToxicology、Microchemical Journal等中药分析与药效物质等领域SCI期刊上发表论文三十余篇。获得2022年广西科技进步奖二等奖1项（排名第五）。担任广西师范大学学报（自然科学版）青年编委以及Journal of Ethnopharmacology等期刊审稿人。
研究方向
1）中药药效物质基础研究；
2）天然药物活性成分的发现及其体内外代谢过程，作用靶标研究。
学历背景
2006-2011 南京中医药大学 中药学（中药药理，五年制）本科；
2012-2015 南京中医药大学 中药学硕士
2015-2018 中国药科大学 生药学博士
工作经历
2018年7月至今 广西师范大学 化学与药学学院
论著专利
2025年度论文发表情况:
1.Zou QF, Chen DJ, Liu CJ, Chen ZH,Yang X,Xu RH,Zhou ZH, Chen JX, Shi W*,Zhang FX*. Combination of Metabolite Analysis and Network Pharmacology toExplore the Potential Anticough Mechanism of Protopine—A Marker in Zhi-Ke-BaoTablets. Rapid Commun Mass Spectrom.2025, 39:e10012.
2.Yang YD, Chen ZH, Li JJ, Yang X, Shi W*, Liang H*, Zhang FX*.Traditional Chinese medicine preparation Shuang-Huang-Lian in the treatment ofinfluenza: a review. J Ethnopharmacol. 2025,119704.
3.Li JJ, Chen ZH, Liang WT, Yang YD, XieTY, Chen DJ, Yang X, Wu PL, Liang XW, Zou HP, Zhang JH*, Shi W*, Zhang FX*. Xiao-Chai-Hu granule alleviatesinfluenza virus-induced pneumonia by regulating TLR4-PI3K-Akt/p38 MAPK-NF-κBpathways. J Ethnopharmacol. 2025,119760.
4.Chen ZH, Li JJ, Liu CJ, Chen DJ, Yang YD,Xie TY, Liang WT, Tu XP, Shi W, YangX*, Chen ZF*, Zhang FX*. Lan-Qinoral liquid alleviates influenza A virus-induced acute lung injury byregulating monocyte-derived macrophages and TLR4/PI3K/AKT/NF-κB signalpathways. J Ethnopharmacol. 2025,119787.
2022-2024年度论文发表情况:
1.Luo FH, Chen ZH, Zeng FF, Yang X, Li JJ,Zhang FX*, Shi W*. Botany, phytochemistry, pharmacologic activities,traditional applications, pharmacokinetics, quality control and toxicity ofZanthoxyli Radix: An updated review. J Ethnopharmacol. 2024, 337(Pt 1):118783.
2.Zeng FF, Chen ZH, Luo FH, Liu CJ, Yang X,Zhang FX*, Shi W*. Sophorae tonkinensis radix et rhizoma: A comprehensivereview of the ethnopharmacology, phytochemistry, pharmacology,pharmacokinetics, toxicology and detoxification strategy. J Ethnopharmacol. 2024,337(Pt1):118784.
3.Ruan YJ, Wang GW, Chen ZH, Tu XP, Han CB,Shi W, Liu JH*, Zhang FX*. Dissectionof potential anti-osteoporosis mechanism of isopsoralen - a quality controlmarker in Psoraleae Fructus - by metabolite profiling and network pharmacology.Rapid Commun Mass Spectrom. 2024,38(19):e9880.
4.Tu XP, Wu SX, Li MY, Chen ZH, Liu CJ,Ruan YJ, Zeng JB, Shi W, Liu JH*, Zhang FX*. Characterization ofmetabolic features and potential anti-osteoporosis mechanism of pinoresinoldiglucoside using metabolite profiling and network pharmacology. Rapid CommunMass Spectrom. 2024,38(19):e9872.
5.Chen DJ, Liu CJ, Chen ZH, Li JJ, Shi W, Zhang QM, Yang X*, Chen JX*, Zhang FX*. Chemicalprofiling of Zhi-Ke-Bao pills and its potential mechanism against cough byultra-high performance liquid chromatography coupled to quadrupoletime-of-flight mass spectrometry and network pharmacology. J Pharm Biomed Anal.2024,247:116257.
6. Rao SW, Liu CJ, Liang D, Duan YY, ChenZH, Li JJ, Pang HQ, Zhang FX*, Shi W*.Multi-omics and chemical profiling approaches to understand the materialfoundation and pharmacological mechanism of Sophorae Tonkinensis Radix etRhizome-induced liver injury in mice. J Ethnopharmacol. 2024,118224.
7. Li JJ, Chen ZH, Liu CJ, Kang YS, Tu XP,Liang H*, Shi W*, Zhang FX*. Thephytochemistry, pharmacology, pharmacokinetics, quality control, and toxicityof Forsythiae Fructus : An updated systematic review. Phytochemistry,2024,114096.
8. Liu CJ, Li HX, Chen ZH, Li JJ, Shi W*, Zhang FX*. A review of theethnopharmacology, phytochemistry, pharmacology, pharmacokineticsand toxicologyof Abri Herba (Ji-Gu-Cao). Phytochemistry, 2024, 221,114064.
9. Chen ZH, Zou QF, Jiang LJ, Liu CJ, LiJJ, Shi W*, Chen ZF*, Zhang FX*. Thecomparative analysis of Lonicerae Japonicae Flos and Lonicerae Flos: Asystematical review. J Ethnopharmacol. 2024,323:117697.
10. Rao SW, Zhang FX, Duan YY, Chen ZH,Liang D*, Shi W*. Urea-based deepeutectic solvents enzyme system for high efficiency extraction of alkaloids andflavonoids in plants:Zanthoxylum nitidum(Roxb.)DC.as a case. Microchem J.2024,199:109964.
11. Liu CJ, Li HX, Zhang YM, Shi W*, Zhang FX*. Dissection of theantitumor mechanism of tetrandrine based on metabolite profiling and networkpharmacology. Rapid Commun Mass Spectrom.2024，38:e9662.
12. Rao SW, Duan YY, Zhao DS, Liu CJ, XuSH, Liang D, Zhang FX*, Shi W*.Integrative Analysis of Transcriptomic and Metabolomic Data for Identificationof Pathways Related to Matrine-Induced Hepatotoxicity. Chem Res Toxicol. 2022,35(12):2271-2284.
13. Rao SW, Duan YY, Pang HQ, Xu SH, Hu SQ,Cheng KG, Liang D, Zhang FX*, Shi W*.Spectrum-effect relationship analysis of bioactive compounds in Zanthoxylumnitidum (Roxb.) DC. by ultra-high performance liquid chromatography massspectrometry coupled with comprehensive filtering approaches. Front Pharmacol,2022, 13: 794277.
科研项目
1）主持国家自然科学基金地区科学基金项目1项（32万）；
2）主持广西自然科学基金面上项目1项（10万）；
3）主持完成广西自然科学基金青年项目1项（8万）；
4）主持完成广西高校中青年教师科研基础能力提升项目1项（3万）；
5）主持省部共建药用资源化学与药物分子工程国家重点实验室人才引进项目1项（50万）。