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        陈振锋，广西师范大学学术委员会副主任、化学与药学学院院长、省部共建药用资源化学与药物分子工程国家重点实验室/教育部重点实验室副主任（兼）、二级教授、博士生导师、广西化学化工学会副理事长；广西政协第十二届、十三届委员、广西政府督学；国家百千万人才工程国家级人选和国家有突出贡献中青年专家、享受国务院政府特殊津贴专家；教育部创新团带头人、教育部新世纪优秀人才支持计划人选、八桂学者。主要从事中药活性成分金属药物化学研究，主持973计划课题1项、国家自然科学基金项目6项（含面上项目4项）、教育部创新研究团队项目2项（含滚动支持1项）、广西自然科学基金创新团队项目等10项。在J. Am. Chem.Soc., Angew. Chem. Int. Ed.,Coordin. Chem. Rev., J. Med. Chem., Eur. J. Med. Chem., CCS Chem.等发表SCI论文260余篇，H指数45；2022-2025年入围全球前2%顶尖科学家榜单。获广西科学技术奖特别贡献奖和科技进步奖一等奖各1项（均排名二）、自然科学奖二等奖2项（排名三和四）。

基于中药活性成分金属抗肿瘤药物、抗糖尿病药物的研究。

1. Hui-Chao Lin†, Wen-Ying Shen†, Jian-Hua Wei†, Liu-Lin Chen, Chun-Peng Jia, Zu-Yu. Mo,Li-Xia Wang, Cheng Hou, Yang-Han Liu, Jihu Su, Hong Liang*, Zhen-Feng Chen*. Rhodium(III)-nitroxyl radical complex triggers dual-pronged disulfidptosis-apoptosis in hepatocellular carcinoma via metabolic sabotage and redox catalysis. Angewandte Chemie International Edition, 2026, 65, e17864.

2. Kun Yang, Qi-Yuan Yang, Kai-Jie Yang,Wu-Yan Yang, Juan Hou, Qian Chen,Yun-Qiong Gu, Muhammad Iqbal Choudhary, Hong Liang*, Zhen-Feng Chen*. Oxoaporphine-metformin Rhodium(III) mixed complex achieving dual antidiabetes and anticancer effects by interfering with glucose metabolism Reprogramming. Journal of the American Chemical Society, 2025, 147 (49), 45145-45156.

3. Hazrat Bilal, Sana Zahoor, Muhammad Iqbal Choudhary, Farzana Shaheen, Sukanya Dej-adisai, Hong Liang*, Zhen-Feng Chen*. Carboxylate embedded metal organic frameworks for potential applications in drug delivery and controlled release. Coordination Chemistry Reviews, 2025, 538, 216688-216717.

4. Qi-Yuan Yang†, Rui Ma†, Yun-Qiong Gu†, Xiao-Fang Xu, Zhen-Feng Chen*, Hong Liang*. Arene-ruthenium(II)/osmium(II) complexes potentiate the anticancer efficacy of metformin via glucose metabolism reprogramming. Angewandte Chemie International Edition, 2022, 61, e202208570.

5. Ye Xu†, Chaojie Tang†, Guang Deng, Chao Li, Zhaoyang Liu, Zhen-Feng Chen, Xiaoyu Wu, Wu Wang*, Zhao-Xi Wang*, Jonathan L. Sessler*. Superhydrophilic FeIV2MnII nanocluster: a combined diagnostic and therapeutic agent. Angewandte Chemie International Edition, 2025, 64, e202512874.

6. Kun Yang, Qian Chen, Juan Chen, Lu-Fei Geng, Meng-Xue Ma, Yun-Qiong Gu, Choudhary Muhammad Iqbal, Hong Liang*, Zhen-Feng Chen*. Copper(II) Complexes of Pyrazolopyrimidine Derivatives as Anticancer Agents with Enhanced Chemodynamic Therapy through Bimodal Apoptosis and Ferroptosis,  ournal of Medicinal Chemistry, 2025, 68(7), 7137-7152.

7. Xing Lu, Mei-Feng Wu, Jiang-Lun Wu, Hai-Qun Zhang, Hong Liang*, Zhen-Feng Chen*. Platinum-based Mcl‑1 inhibitor targeting mitochondria achieves enhanced antitumor activity as a single agent or in combination with ABT-199. Journal of Medicinal Chemistry, 2023, 66(13), 8705−8716.

8. Yun-Qiong Gu, Kun Yang, Qi-Yuan Yang, Huan-Qing Li Mei-Qi Hu, Meng-Xue Ma, Nan-Feng Chen, Yang-Han Liu, Hong Liang*, Zhen-Feng Chen*. Rhodium(III)-Picolinamide Complexes Act as Anticancer and Antimetastasis Agents via Inducing Apoptosis and Autophagy. Journal of Medicinal Chemistry, 2023, 66(14), 9592-9606.

9. Wen-Ying Shen, Chun-Peng Jia, Li-Yi Liao, Liu-Lin Chen, Cheng Hou, Yang-Han Liu, Hong Liang*, Zhen-Feng Chen*. Copper(II) complexes of halogenated quinoline schiff base derivatives enabled cancer therapy through glutathione-assisted chemodynamic therapy and inhibition of autophagy flux.  Journal of Medicinal Chemistry, 2022, 65, 5134-5148.

10. Xing Lu, Yan-Cheng Liu, Chris Orvig, Hong Liang*, Zhen-Feng Chen*. Discovery of a copper-based Mcl1 inhibitor as an effective antitumor agent, Journal of Medicinal Chemistry, 2020, 63, 9154–9167.

11. Zhen-Feng Chen*, Qi-Pin Qin, Jiao-Lan Qin, Yan-Cheng Liu, Ke-Bin Huang, Yu-Lan Li, Ting Meng, Guo-Hai Zhang, Yan Peng, Xu-Jian Luo, Hong Liang*. Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Tumor Cell Apoptosis by Organoplatinum(II) Complexes with Oxoisoaporphine. Journal of Medicinal Chemistry, 2015, 58(5), 2159-2179.

12. Zhen-Feng Chen*, Qi-Pin Qin, Jiao-Lan Qin, Jie Zhou, Yu-Lan Li, Nan Li, Yan-Cheng Liu, Hong Liang*. Anticancer Activity by Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Induction of Tumor Cell Apoptosis. Journal of Medicinal Chemistry, 2015, 58(11), 4771-4789.

13. Lan-Shan Liao, Yin Chen, Zu-Yu Mo, Cheng Hou*, Gui-Fa Su*, Hong Liang, Zhen-Feng Chen*. Ni(II), Cu(II) and Zn(II) complexes with the 1-trifluoroethoxyl-2,9,10-trimethoxy-7-oxoaporphine ligand simultaneously target microtubules and mitochondria for cancer therapy. Inorganic Chemistry Frontiers, 2021,8(9), 2225-2247.

14. Noor Shad Gul†, Taj-Malook Khan†, Yan-Cheng Liu, Muhammad Iqbal Choudhary, Zhen-Feng Chen*, Hong Liang*. Pd(II) and Rh(III) complexes with isoquinoline derivatives induced mitochondria-mediated apoptotic and autophagic cell death in HepG2 cells, CCS Chemistry, 2020, 2, 1626-1641.

15. Ke-Bin Huang*, Feng-Yang Wang, Hai-Wen Feng, He-Jiang Luo, Yan Long, Tao-Tao Zou, Chan Albert S. C., Rong Liu, Hua-Hong Zou*, Zhen-Feng Chen*, Yan-Cheng Liu, You-Nian Liu, Hong Liang*. An aminophosphonate ester ligand-containing platinum(II) complex induces potent immunogenic cell death in vitro and elicits effective anti-tumour immune responses in vivo. Chemical Communications, 2019, 55(87), 13066-13069.

16. Qi-Pin Qin, Jiao-Lan Qin, Ting Meng, Gui-Ai Yang, Zu-Zhuang Wei, Yan-Cheng Liu, Hong Liang*, Zhen-Feng Chen*. Preparation of 6/8/11-amino/chloro-oxoisoaporphine and group-10 metal complexes and evaluation of their in vitro and in vivo antitumor activity. Scientific Reports, 2016, 6, 37644-37671.

17. Zhen-Feng Chen*, Yun-Qiong Gu, Xiao-Yan Song, Yan-Cheng Liu, Yan Peng, Hong Liang*. Synthesis, crystal structure, cytotoxicity and DNA interaction of 5,7-dichloro-8- quinolinolato-lanthanides. European Journal of Medicinal Chemistry, 2013, 59, 194-202.

18. Zhen-Feng Chen*, Yan Peng, Yun-Qiong Gu, Yan-Cheng Liu, Mei Liu, Ke-Bin Huang, Kun Hu and Hong Liang*. High antitumor activity of 5,7-dihalo-8- quinolinolato tin(IV) complexes. European Journal of Medicinal Chemistry, 2013, 2013, 62,51-58.

19. Hazrat Bilal, Cai-Xiang Zhang, Muhammad Iqbal Choudhary, Sukanya Dej-adisai, Yanghan Liu*, Zhen-Feng Chen*. Copper(II) carboxylate complexes inhibit Staphylococcus aureus biofilm formation by targeting extracellular proteins. Journal of Inorganic Biochemistry, 2025, 266, 112835.

20. Zhen-Feng Chen*, Yan-Fang Shi, Yan-Cheng Liu, Xue Hong, Bo Geng, Yan Peng, and Hong Liang*. TCM active ingredient oxoglaucine metal complexes: crystal structure, cytotoxicity, and interaction with DNA. Inorganic Chemistry, 2012, 51, 1998-2009.

1. 国家自然科学基金面上项目：靶向糖代谢重编程具有抗肿瘤和降糖双重活性的二甲双胍/-小檗碱和氧化阿朴菲混配钌、铑、锇配合物及其与PD-1/PD-L1抗体联用研究（22477018），2025/1-2028/12，50万元。

2. 国家自然科学基金面上项目：咔啉生物碱金属配合物作为强效选择性Mcl-1抑制剂的发现及其与Bcl-2抑制剂venetoclax联用抗肿瘤活性研究（22077022），2021/1-2024/12，63万元。

3. 国家自然科学基金面上项目：雌激素靶向配体调控的高活性卤代喹啉-镧系系列抗肿瘤配合物（21271051），2013/1-2016/12，78万元。

4. 教育部创新团队项目：天然活性物质的发现、结构改造与功能（IRT1225）, 2013/1-2015/12，450万元；滚动支持（IRT_16R15）2017/1-2019/12，300万元。

5. 广西首批八桂学者项目：药物化学，2011/11-2025/9，300万元。

6. 广西中央引导地方发展科技发展专项：靶向Mcl-1和诱导ICD效应的瑶药活性成分生物碱金属抗肿瘤配合物研究（2022ZYZX1075）， 2022/10-2026/5，50万元。

7. 广西自然科学基金重点项目: 强效选择性Mcl-1咔啉生物碱金属配合物抑制剂的发现及其与Bcl-2 抑制剂ABT-199联用抗肿瘤活（2023GXNSFDA026054）， 2023/6-2026/5，30万元。

8. 广西自然科学基金重点项目: 基于中药活性成分氧化阿朴菲生物碱抗肿瘤金属药物前期研究（2012GXNSFDA053005）， 2012/4-2014/3，25万元。