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叶芳贵 

点击数:9686 来源:化学与药学学院 作者: 录入:人员机构 更新时间:2021-11-16

叶芳贵 [教授]




叶芳贵

联系方式

办公电话:5846279

手机号码:

电子邮箱:fgye@gxnu.edu.cn

办公地址:化学楼210

基本介绍

叶芳贵,男,福建建瓯人,1974年生,博士,广西师范大学二级教授,博士生导师,广西自然科学杰出青年基金获得者。主要从事纳米酶及纳米多孔分离材料研究。先后主持国家自然科学基金5项、广西自然科学基金5项获科技奖励三项:2022年广西自然科学奖一等奖(第一完成人),2014年广西自然科学奖一等奖(第四完成人),以2010年广西自然科学奖二等奖(第二完成人)。迄今,以第一作者或通讯作者在Anal. Chem., Biosens. Bioelectron., ACS Appl. Mater. Interfaces, Chem. Commun., Chem. Eur. J., J. Mater. Chem. B, J. Chromatogr. A, Anal. Chim. ActaAnaylst, Sensor Actuat. B-Chem., Talanta SCI源刊物上发表论文90余篇,H指数:38 (Google Scholar),获授权中国发明专利5项。

研究兴趣

1. 纳米酶的设计合成及其生物传感分析

2. 纳米酶的抗菌及抗肿瘤机理与应用

3. 多孔分离材料(MOF/COF)在样品前处理中的应用

学历背景

2001.09~2006.07 福州大学化学化工学院分析化学专业硕博连读,博士

1993.09~1997.07 南开大学化学学院化学专业,本科

工作经历

2011.01~至今  广西师范大学化学与药学学院,教授

2007.012010.12 广西师范大学化学化工学院,副教授

2006.07~2006.12 广西师范大学化学化工学院,讲师

1997.07~2001.08 福州福抗药业集团股份有限公司,助理工程师

讲授课程

主讲分析化学、仪器分析、药物分析及药物分析化学等课程。

发表论文

92. Jia Wu, Ling Liang, Shuishi Li, Yuan Qin, ShulinZhao, Fanggui Ye*. MOF derivatization of multifunctional nanozyme: Peroxidase-like catalytic activity combined with magnetic solid phase extraction for colorimetric detection of Hg2+. Spectrochim. Acta A Mol. Biomol. Spectrosc. 2024, DOI: https://doi.org/10.1016/j.saa.2024.124392.

91. Jia Wu, Ling Liang, Shuishi Li, Yuan Qin, Shulin Zhao, Fanggui Ye*. Rational design of nanozyme with integrated sample pretreatment for colorimetric biosensing. Biosens. Bioelectron. 2024, 257, 116310.

90. Yuan Qin, Shuishi Li, Ling Liang, Jia Wu, Yuhui Zhu, Shulin Zhao and Fanggui Ye*. Regulating the redox and non-redox enzyme-mimicking activities of Ce-UiO-66-NO2 nanozyme for dual-mode sensing of phosphate. Sensor Actuat. B-Chem. 2024, 412, 135782.

89. Shuishi Li, Yanbiao Pan, Manjing Li, Shu-Hui Li*, Shulin Zhao and Fanggui Ye*. Rational design of cuprofullerene bipyridine nanozyme with high peroxidase-like activity for colorimetric sensing of bleomycin. Anal. Bioanal. Chem. 2024, DOI:10.1007/s00216-024-05234-8

88. Shuishi Li, Manjing Li, Yanbiao Pan, Shu-Hui Li*, Shulin Zhao, Fanggui Ye*. Synergistic effectof fullerenol and light enhanced the peroxidase-like activity of Fe(III) for colorimetric detection of deferasirox. Sensor Actuat. B-Chem. 2024, 407, 135470.

87. Lianguo Geng, Xingdi Sun, Liuding Wang, Fengping Liu, Shengqiang Hu*, Shulin Zhao and Fanggui Ye*. Analyte-induced laccase-mimicking activity inhibition and conductivity enhancement of electroactive nanozymes for ratiometric electrochemical detection of thiram. J. Hazar. Mater. 2024, 463, 132936.

86. Yan Duan, Ling Liang, Fanggui Ye* and Shulin Zhao*. Ce-MOF@polydopamine composite nanozyme as an efficient scavenger for reactive oxygen species and iron in thalassemia disease therapy. Nanoscale 2023, 15,13574.

85. Ling Liang, Yuting Jiang, Fengping Liu, Shuishi Li, Jia Wu, Shulin Zhao and Fanggui Ye*. Three-in-one covalent organic framework nanozyme: Self-reporting, self-correcting and light-responsive for fluorescence sensing 3-nitrotyrosine. Biosens. Bioelectron. 2023, 237, 115542.

84. Yuan Qin, Shuishi Li, Ling Liang, Shulin Zhao and Fanggui Ye*. Rational synthesis of FeNiCo-LDH nanozyme for colorimetric detection of deferoxamine mesylate. Spectrochim. Acta A Mol. Biomol. Spectrosc. 2023, 237, 123156.

83. Shuishi Li, Ling Liang, Longfei Tian, Jia Wu, Yuhui Zhu, Yuan Qin, Shulin Zhao and Fanggui Ye*. Enhanced peroxidase-like activity of MOF nanozyme by co-catalysis for colorimetric detection of cholesterol. J. Mater. Chem. B 2023, 11, 7913-7919.

82. Lianguo Geng, Shengqiang Hu*, Fengping Liu, Lu Liu, Xin He, Yangcan Wang, Yuhui Zhu, Hui Xu, Shulin Zhao and Fanggui Ye*. MOF-derived magnetic trimetallic oxide-carbon nanocomposites for modification-free and dual molecular events-dependent ratiometric electrochemical analysis of intracellular glutathione. Sensor Actuat. B-Chem. 2023, 390, 134010.

81. Shuishi Li, Yanyan Cheng, Ling Liang, Shulin Zhao and Fanggui Ye*. Rational design of ZIF-67 derived hollow nanozyme through a general strategy for biosensing. Microchem. J. 2023, 93, 108601.

80. Yuhui Zhu, Xueting Fang, Xiaofei Lv, Meijun Lu, Hui Xu, Shengqiang Hu, Shulin Zhao and Fanggui Ye*. A single aptamer-dependent sandwich-type biosensor for the colorimetric detection of cancer cells via direct coordinately binding of bare bimetallic metal-organic framework-based nanozymes. Biosensors 2023, 13, 225.

79. Ling Liang, Yuting Jiang, Fengping Liu, Jia Wu, Longfei Tian, Shulin Zhao and Fanggui Ye*. Smartphone flashlight-triggered covalent organic framework nanozyme activity: A universal scheme for visual point-of-care testing. Sensor Actuat. B-Chem. 2023, 381, 133422.

78. Yuhao Xiong, Linjing Su, Zhi Zhang, Shulin Zhao and Fanggui Ye*. Dipeptide surface modification and ultrasound boosted phosphatase-like activityof the ceria nanozyme: Dual signal enhancement for colorimetric sensors. ACS Sustainable Chem. Eng. 2023, 11, 525-535.

77. Fengping Liu, Wei Huang, Lianguo Geng, Shulin Zhao and Fanggui Ye*. Highly sensitive photoelectrochemical detection of cancer biomarkers based on CdS/Ni-CAT-1 nanorod arrays Z-scheme heterojunction with spherical nucleic acids-templated copper nanoclustersas signal amplification. Sensor Actuat. B-Chem. 2023, 374, 132786.

76. Yuhao Xiong, Linjing Su, Yan Peng*, Shulin Zhao and Fanggui Ye*. Dextran-coated Gd-based ultrasmall nanoparticles as phosphatase like nanozyme to increase ethanol yield via reduction of yeast intracellular ATP level. J. Colloid Interf. Sci. 2022, 627, 405-414.

75. Wei Tan, Li Zhu, Longfei Tian, Hongfeng Zhang, Rongfei Peng, Kuncai Chen*, Shulin Zhao and Fanggui Ye*. Preparation of cationic hierarchical porous covalent organic frameworks for rapid and effective enrichment of perfluorinated substances in dairy products. J. Chromatogr. A 2022, 1675, 463188.

74. Tianran Lin*, Ying Sun, Chunsuo Tian, Di Wang, Li Hou*, Fanggui Ye* and ShulinZhao. A silk-like hydrogen-bonded organic framework functionalized membrane with intrinsic catalytic activity for nonmetallic reduction of 4-nitrophenol. Chem. Eng. J. 2022,  441, 136092.

73. Ling Liang, Yuhao Xiong,Yan Duan, Weiyuan Zuo, Li Liu, Fanggui Ye* and Shulin Zhao. Colorimetric detection of creatinine based on specifically modulating the peroxidase mimicking activity of Cu-Fenton system. Biosens. Bioelectron. 2022, 206, 114121.

72. Yuhao Xiong, Linjing Su, Fanggui Ye* and Shulin Zhao. Ultrasmall phosphatase-mimicking nanoceria with slight self-colour for nonredox nanozyme-based colorimetric sensing. Anal. Chim. Acta 2022, 1200, 339604.

71. Ling Liang#, Yan Duan#, Yuhao Xiong, Weiyuan Zuo, Fanggui Ye* and Shulin Zhao*. Synergistic cocatalytic effect of MoO3 and creatinine on Cu-Fenton reactions for efficient decomposition of H2O2. Mater. Today Chem. 2022, 24, 100805.

70. Changzhi Hu, Yuhao Xiong, Ling Liang,Weiyuan Zuo, Fanggui Ye* and Shulin Zhao. Enhancing theperoxidase-like activity of MIL-88B by ligand exchange with polydopamine. Dalton Trans. 2022, 51, 2262-2268.

69. Li Hou, YuanlinHuang, Tianran Lin*, Fanggui Ye* and Shulin Zhao. A FRET ratiometric fluorescence biosensor for the selective determination of pyrophosphate ion and pyrophosphatase activity based on difunctional Cu-MOF nanozyme. Biosensors and Bioelectronics: X 2022, 10, 100101.

68. Fengping Liu, Lianguo Geng, Fanggui Ye* and Shulin Zhao. MOF-derivated MnO@C nanocomposite with bidirectional electrocatalytic ability as signal amplification for dual-signal electrochemical sensing of cancer biomarker. Talanta 2022, 239, 123150.

67. Yuhao Xiong, Linjing Su, Fanggui Ye* and Shulin Zhao. Inhibition of NADP(H) supply by highly active phosphatase-like ceria nanozymes to boost oxidative stress and ferroptosis. Mater. Today Chem.  2022, 23, 100672.

66. Shengqiang Hu*, Xueting Fang, Guijing Liu, Guixiang Ma, Fanggui Ye* and Shulin Zhao. Gas pressure-assisted ratiometric atomic flame assay for point of-care testing of tumor cell-derived exosomes. Analyst 2022,147, 48-54.

65. Yuhao Xiong, Linjing Su, Fanggui Ye* and Shulin Zhao. Porous oxyhydroxide derived from metal-organic frameworks as efficient triphosphatase-like nanozyme for chromium(iii) ion colorimetric sensing. ACS Appl. Bio Mater. 2021, 4, 6962-6973.

64. Weiyuan Zuo, Ling Liang, Fanggui Ye* and Shulin Zhao. An integrated platform for label-free fluorescence detection and inactivation of bacteria based on boric acid functionalized Zr-MOF. Sensor Actuat. B-Chem. 2021, 345, 130345.

63. Weiyuan Zuo, Ling Liang, Fanggui Ye* and Shulin Zhao. Construction of visible light driven silver sulfide/graphitic carbon nitride p-n heterojunction for improving photocatalytic disinfection. Chemosphere 2021, 283, 131167.

62. Wei Tan, Xianyan Xu*, Yuanxia Lv, Wenjuan Lei, Kun Hu, Fanggui Ye* and Shulin Zhao. Sulfonic acid functionalized hierarchical porous covalent organic frameworks as a SALDI-TOF MS matrix for effective extraction and detection of paraquat and diquat. J. Colloid Interf. Sci. 2021, 603, 172-181.

61. Yanyan Cheng, Ling Liang, Fanggui Ye* and Shulin Zhao. Ce-MOF with intrinsic haloperoxidase-like activity for ratiometric colorimetric detection of hydrogen peroxide. Biosensors 2021, 11, 204.

60. Ying Sun, Tianran Lin*, Cuihong Zeng, Gaoyan Jiang, Xuanhan Zhang, Fanggui Ye* and Shulin Zhao. A self-correcting fluorescent assay of tyrosinase based on Fe-MIL-88B-NH2 nanozyme. Microchim. Acta 2021, 188, 158

59. Xueting Fang, Xiaoting Zhang, Zhihua Zhang, Shengqiang Hu*, Fanggui Ye* and Shulin Zhao. Complementary atomic flame/molecular colorimetry dual-mode assay for sensitive and wide-range detection of cancer cells. Chem. Commun. 2021, 57, 3327-3330

58. Ling Liang, Zhenghong Zhao, Fanggui Ye* and Shulin Zhao. Rapid and sensitive colorimetric detection of dopamine based on the enhanced-oxidase  mimicking activity of cerium (Ⅳ). New J. Chem. 2021, 45, 6780-6786

57. Wei Tan, Xiaohai Wu, Wenren Liu, Fanggui Ye* and Shulin Zhao. Synchronous constructionof hierarchical porosity and thiol functionalization in COFs for selective extraction of cationic dyes in water samples. ACS Appl. Mater. Interfaces 2021, 13, 4352-4363.

56. Xiaohai Wu, Siyu Si, Wei Tan, Xin Lu, Fanggui Ye* and Shulin Zhao. Preparation of magnetic mesoporous metal-phenolic coordination spheres for extraction of crystal violet and leuco-metabolites in fish. J. Chromatogr. A 2021, 1636, 461776.

55.Wei Tan, Tao Chen,Wenren Liu, Fanggui Ye* and Shulin Zhao. Design and fabrication of boric acid functionalized hierarchical porous metal-organic frameworks for specific removal of cis-diol containing compounds from aqueous solution. Appl. Surf. Sci. 2021, 53, 147714.

54. Ling Liang,  Yaojing Huang,  Wenren Liu,  Weiyuan Zuo,  Fanggui Ye* and Shulin Zhao. Colorimetric detection of salicylic acid in aspirin using MIL-53(Fe) nanozyme. Front. Chem. 2020, 8, 671.

53. Li Hou, Yuemei Qin, Tianran Lin*, Ying Sun, Fanggui Ye* and Shulin Zhao. Michael reaction-assisted fluorescent sensor for selective and one step determination of catechol via bifunctional Fe-MIL-88NH2 nanozyme. Sensor Actuat. B-Chem. 2020, 321, 128547.

52. Zhenghong Zhao, Yaojing Huang, Wenren Liu, Fanggui Ye* and Shulin Zhao. Immobilized glucose oxidase on boronic acid-functionalized hierarchically porous MOF as an integrated nanozyme for one-step glucose detection. ACS Sustainable Chem. Eng. 2020, 8, 4481-4488.

51. Wenqian Wu, Feng Lin, Xiaohan Yang, Bin Wang, Xin Lu*, Qiuxia Chen, Fanggui Ye* and Shulin Zhao. Facile synthesis of magnetic carbon nanotubes derived from ZIF-67 and application to magnetic solid-phase extraction of profens from human serum. Talanta 2020, 207, 120284

50. Kun Hu, Yuanxia Lv, Fanggui Ye*, Tao Chen and Shulin Zhao*. Boric-acid-functionalized covalent organic framework for specific enrichment and direct detection of cis-diol-containing compounds by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Anal. Chem. 2019, 91, 6353-6362.

49. Zhenghong Zhao, Junhong Pang, Wenren Liu, Tianran Lin, Fanggui Ye* and Shulin Zhao. A bifunctional metal organic framework of type Fe(III)-BTC for cascade (enzymatic and enzyme-mimicking) colorimetric determination of glucose. Microchim. Acta 2019, 186, 295

48. Zhenghong Zhao, Tianran Lin*, Wenren Liu, Li Hou, Fangui Ye* and Shulin Zhao. Colorimetric detection of blood glucose based on GOx@ZIF-8@Fe-polydopamine cascade reaction. Spectrochim. Acta A Mol. Biomol. Spectrosc. 2019, 219, 240-247.

47. Yuanlin Huang, Guangzhao Liang, Tianran Lin*, Li Hou, Fanggui Ye* and Shulin Zhao. Magnetic Cu/Fe3O4@FeOOH with intrinsic HRP-like activity at nearly neutral pH for one-step biosensing. Anal. Bioanal. Chem. 2019, 411, 3801-3810.

46. Yuanlin Huang, Tianran Lin*, Li Hou, Fanggui Ye* and Shulin Zhao. Colorimetric detectionof thioglycolic acid based on the enhanced Fe3+ ions Fenton reaction. Microchem. J. 2019, 144, 190-194.

45. Yan Duan, Fanggui Ye*, Yuanlin Huang, Yuemei Qin, Caimei He and Shulin Zhao*. One-pot synthesis of metal-organic framework-based drug carrier for intelligent glucose-responsive insulin delivery. Chem. Commun. 2018, 54, 5377-5380.  

44. Tianran Lin, Yuemei Qin, Yuanlin Huang, Ruitao Yang, Li Hou, Fanggui Ye* and Shulin Zhao. A label-free fluorescence assay for hydrogen peroxide and glucose based on the bifunctional MIL-53(Fe) nanozyme. Chem. Commun. 2018, 54, 1762-1765

43. Haiguan Yang, Ruitao Yang, Peng Zhang, Yuemei Qin, Tao Chen and Fanggui Ye*. A bimetallic (Co/2Fe) metal-organic framework with oxidase and peroxidase mimicking activity for colorimetric detection of hydrogen peroxide. Microchim. Acta 2017, 184, 4629-4635

42. Tao Chen, Cong Zhang, Yuemei Qin, Haiguan Yang, Peng Zhang and Fanggui Ye*. Preparation of cationic MOFs with mobile anions by anion stripping to remove 2,4-D from water. Materials 2017, 10, 879-890

41. Yuhao Xiong, Yuemei Qin, Linjing Su and Fanggui Ye*. Bioinspired synthesis of Cu2+-modified covalent triazine framework: A new highly efficient and promising peroxidase mimic. Chem. Eur. J. 2017, 23, 11037-11045

40. Jiannan Wang, Shufen Shen, Xin Lu and Fanggui Ye*. One-pot preparation of an organic polymer monolith by thiol-ene click chemistry for capillary electrochromatography. J. Sep. Sci. 2017, 40, 3144-3152

39. Haiguan Yang, Junqi Zha, Peng Zhang, Yuemei Qin, Tao Chen and Fanggui Ye*. Fabrication of CeVO4 as nanozyme for facile colorimetric discrimination of hydroquinone from resorcinol and catechol. Sensor Actuat. B-Chem. 2017, 247, 469-478

38. Fan Nie, Jiannan Wang, Xin Lu* and Fanggui Ye*. Preparation of bifunctional magnetic nanoparticles with octadecyl and phosphate group by thiol-ene click chemistry for extraction and enrichment of organophosphorus pesticides in tea drink. Anal. Methods 2017, 9, 2069-2075

37. Tao Chen, Yuhao Xiong, Yuemei Qin, Haiguan Yang, Peng Zhang and Fanggui Ye*. Facile synthesis of low-cost biomass-based γ-Fe2O3/C for efficient adsorption and catalytic degradation of methylene blue in aqueous solution. RSC Adv. 2017, 7, 336-343

36. Peng Zhang, Haiguan Yang, Tao Chen, Yuemei Qin and Fanggui Ye*. Facile one-pot preparation of a novel imidazolium-based monolith by thiol–ene click chemistry for capillary liquid chromatography. Electrophoresis 2017, 38, 3013-3019

35. Junyu Lu, Fanggui Ye*, Xiuxiang Huang, Lianqiang Wei, Dongmei Yao, Shengying Li, Miao Ouyang and Hongfang Lai. Ionic liquid-modified magnetic nanoparticles as solid phase extraction adsorbent coupled with HPLC for determination of linear alkylbenzene sulfonates in water samples. J. Sep. Sci. 2017, 40, 1133-1341

34. Haiguan Yang, Junqi Zha, Peng Zhang, Yuhao Xiong, Linjing Su and Fanggui Ye*. Sphere-like CoS with nanostructures as peroxidase mimics for colorimetric determination of H2O2 and mercury ions. RSC Adv. 2016, 6, 66963-66970

33. Peng Zhang, Jiannan Wang, Haiguang Yang, Linjing Su, Yuhao Xiong and Fanggui Ye*. Facile one-pot preparation of chiral monoliths with a well-defined framework based on thiol–ene click reaction for capillary liquid chromatography. RSC Adv. 2016, 6, 24835-24842

32. Linjing Su, Yuhao Xiong, Haiguan Yang, Peng Zhang and Fanggui Ye*. Prussian blue nanoparticles encapsulated inside a metal-organic framework via in situ growth as promising peroxidase mimetics for enzyme inhibitor screening. J. Mater. Chem. B 2016, 4, 128-134

31. Junyu Lu, Yuhao Xiong, Chunjin Liao and Fanggui Ye*. Colorimetric detection of uric acid in human urine and serum based on peroxidase mimetic activity of MIL-53(Fe). Anal. Methods 2015, 7, 9894-9899

30. Yuhao Xiong, Linjing Su, Haiguan Yang, Peng Zhang and Fanggui Ye*. Fabrication of copper sulfide using a Cu-based metal organic framework for colorimetric determination and efficient removal of Hg2+ in aqueous solutions. New J. Chem. 2015, 39, 9221-9227

29. Haiguan Yang, Yuhao Xiong, Peng Zhang, Linjing Su and Fanggui Ye*. Colorimetric detection of mercury ions using MnO2 nanorods as enzyme mimics. Anal. Methods 2015, 7, 4596-4601

28. Yuhao Xiong, Siheng Chen, Fanggui Ye*, Lingjing Su, Cong Zhang, Shufen Shen and Shulin Zhao. Synthesis of mixed valence state Ce-MOF as oxidase mimetics for colorimetric detection of biothiols. Chem. Commun. 2015, 51, 4635-4638

27. Shengchao Yang, Fanggui Ye*, Cong Zhang, Shufen Shen and Shulin Zhao. In situ synthesis of metal-organic frameworks in porous polymer monolith as stationary phase for capillary liquid chromatography. Analyst 2015, 140, 2755-2761

26. Cong Zhang, Fanggui Ye*, Shufen Shen, Yuhao Xiong, Linjing Su and Shulin Zhao. From metal-organic frameworks to magnetic nanostructured porous carbon composites: Towards highly efficient dye removal and degradation. RSC Adv. 2015, 5, 8228-8235

25. Yuhao Xiong, Fanggui Ye*, Cong Zhang, Shufen Shen, Linjing Su and Shulin Zhao. Synthesis of magnetic porous γ-Fe2O3/C@HKUST-1 composites for efficient removal of dyes and heavy metal ions from aqueous solution. RSC Adv. 2015, 5, 5164-5172

24. Yuhao Xiong, Siheng Chen, Fanggui Ye*, Linjing Su, Cong Zhang, Shufen Shen and Shulin Zhao. Preparation of magnetic core-shell nanoflowers Fe3O4@MnO2 as reusable oxidase mimetics for colorimetric detection of phenol. Anal. Methods 2015, 7, 1300-1306

23. Shufen Shen, Fanggui Ye*, Cong Zhang, Yuhao Xiong, Linjing Su and Shulin Zhao. Preparation of polyhedral oligomeric silsesquioxane based hybrid monoliths by thiol-ene click chemistry for capillary liquid chromatography. Analyst 2015, 140, 265-271

22. Shengchao Yang, Fanggui Ye*, Qinghui Lv, Cong Zhang, Shufen Shen and Shulin Zhao. Incorporation of metal-organic framework HKUST-1 into porous polymer monolithic capillary columns to enhance the chromatographic separation of small molecules. J. Chromatogr. A 2014, 1360, 143-149

21. Wei Yu, Chen Xia, Yang Sheng-Chao, LV Qing-Hui, Ye Fang-Gui* and Zhao Shu-Lin. Preparation and characterization of polymer solid-phase extraction monolith immobilized metal affinity ligands. Chin. J. Anal. Chem. 2014, 42, 495-500

20. Fanggui Ye, Jinwen Liu, Yong Huang, Shutin Li and Shulin Zhao*. Competitive immunoassay of progesterone by microchip electrophoresis with chemiluminescence detection. J. Chromatogr. B 2013, 936, 74-79

19. Fanggui Ye, Tinzhen Yang, Yong Huang, Shutin Li and Shulin Zhao*. Homogeneous immunoassay of cortisol based on microchip electrophoresis with chemiluminescence detection. Anal. Methods 2013, 5, 5657-5661

18. Aizhu Zhang, Fanggui Ye*, Junyu Lu and Shulin Zhao. Screening α-glucosidase inhibitor from natural products by capillary electrophoresis with immobilised enzyme onto polymer monolith modified by gold nanoparticles. Food Chem. 2013, 141, 1854-1859

17. Junyu Lu, Fanggui Ye*, Aizhu Zhang, Xia Chen, Yu Wei, Shulin Zhao. Preparation and evaluation of ionic liquid-gold nanoparticles functionalized silica monolithic column for capillary electrochromatography. Analyst 2012, 137, 5860-5865

16. Chen Xia, Wei Yu, Lu Jun-Yu, Zhang Ai-Zhu, Ye Fang-Gui* and Zhao Shu-Lin.  Preparation and evaluation of C18 modified capillary open-tubular column based on thiol-ene click chemistry for capillary electrochromatography. Chin. J. Anal. Chem. 2012, 40, 1584-1588.

15. Junyu Lu, Fanggui Ye*, Aizhu Zhang, Zong Wei, Yan Peng and Shulin Zhao. Preparation and characterization of silica monolith modified with bovine serum albumin-gold nanoparticles conjugates and its use as chiral stationary phases for capillary electrochromatography. J. Sep. Sci. 2011, 34, 2329-2336

14. Zhang Ai-Zhu, Ye Fang-Gui*, Lu Jun-Yu, Wei Zong, Peng Yan and Zhao Shu-Lin. preparation and characterization of polymer solid-phase microextraction monolith modified with gold nanoparticle. Chin. J. Anal. Chem. 2011, 39, 1247-1250

13. Ye Fang-Gui*, Lu Jun-Yu, Wang Yuan, Zhang Ai-Zhu, Tian Jian-Niao and Zhao Shu-Lin. Preparation and characterization of gold nanoparticle-modified silica monolith for capillary electrochromatography. Chin. J. Anal. Chem. 2011, 39, 341-345

12. Fanggui Ye*, Baojun Huang, Shun Wang and Shulin Zhao. Electrochromatographic performance of conventional and polar-embedded C16 silica monolithic stationary phases. J. Sep. Sci. 2010, 33, 3386-3392

11. Fanggui Ye*, Hengshan Wang, Baojun Huang and Shulin Zhao. Maleopimaric acid anhydride-bonded silica monolith as chiral stationary phase for separations of phenylthiocarbamyl amino acids by capillary electrochromatography. Electrophoresis 2010, 31, 1488-1492

10. Fanggui Ye, Yong Huang, Qing Xu, Ming Shi and Shulin Zhao*. Quantification of taurine and amino acids in mice single fibrosarcoma cell by microchip electrophoresis coupled with chemiluminescence detection. Electrophoresis 2010, 31, 1630-1636

9. Fanggui Ye, Ming Shi, Yong Huang and Shulin Zhao*. Noncompetitive immunoassay for carcinoembryonic antigen in human serum by microchip electrophoresis for cancer diagnosis. Clin. Chim. Acta 2010, 411, 1058-1062

8. Ye Fang-gui*, Han Yan-yan, Wang Shun, Huang Bao-jun and Zhao Shu-lin. Preparation and characterization of butylaminopropyl silica monolithic column for capillary electrochromatography. Chin. J. Anal. Chem. 2010, 38, 192-196

7. Fanggui Ye*, Shun Wang and Shulin Zhao. Preparation and characterization of mixed-mode monolithic silica column for capillary electrochromatography. J. Chromatogr. A 2009, 1216, 8845-8850

6. Fanggui Ye, Shuting Li and Shulin Zhao*. Electrochromatographic evaluation of diol-bonded silica monolith capillary column for separation of basic compounds. J. Chromatogr. Sci. 2009, 47, 492-496

5. Fanggui Ye, Shuting Li and Shulin Zhao*. Development of a new C14 monolithic silica column containing embedded polar groups for pressurized capillary electrochromatography. J. Sep. Sci. 2007, 30, 3027-3034

4. Fanggui Ye, Zenghong Xie*, Xiaoping Wu and Xucong Lin. Determination of pyrethroid pesticide residues in vegetables by pressurized capillary electrochromatography. Talanta 2006, 69, 97-102

3. Fanggui Ye, Zenghong Xie* and Kwok-Yin Wong. Monolithic silica columns with mixed mode of hydrophilic interaction and weak anionexchange stationary phase for pressurized capillary electrochromatography. Electrophoresis 2006, 27, 3373-3380

2. Fanggui Ye, Zenghong Xie*, Xiaoping Wu, Xucong Lin and Guonan Chen. Separation of polar and basic compounds in hydrophilic interaction pressurized CEC using diethylenetriaminopropyl silica monolithic columns. Chromatographia 2006, 64, 267-272

1. Fanggui Ye, Zenghong Xie*, Xiaoping Wu, Xucong Lin and Guonan Chen*. Phenylaminopropyl silica monolithic column for pressure assisted capillary electrochromatography. J. Chromatogr. A 2006, 1117, 170-175

专利申请

1. 叶芳贵,王恒山,赵书林,黄保军.硅胶毛细管整体手性固定相及其制备方法.中国发明专利,授权专利号ZL200910114704.0

2. 叶芳贵,陆俊宇,张爱珠,赵书林.离子液体硅胶毛细管整体柱固定相的制备方法.中国发明专利,授权专利号:ZL201110343311.4

3. 叶芳贵,张爱珠,陆俊宇,赵书林.一种多孔整体柱固定化酶微反应器的制备方法.中国发明专利,授权专利号:ZL201110343288.9

4. 叶芳贵,沈淑芬,张聪,赵书林.POSS杂化毛细管整体柱固定相及其制备方法中国发明专利,授权专利号:ZL201410282354.X

5. 赵书林,黄勇,叶芳贵,石明,李向堂.微流控芯片化学发光测定人单个血红细胞内物质的方法.中国发明专利,授权专利号:ZL200910114403.8 

科研项目

1.国家自然科学基金区域创新发展联合基金重点项目:纳米酶杂化医用敷料的构筑及应用研究(U23A20686), 2024.1~2027.12,主要参与人

2. 国家自然科学基金:合理设计集成样品前处理功能的纳米酶及其比色传感应用(22064004), 2021.1~2024.12, 主持;

3. 国家自然科学基金:点击反应制备分级孔金属-有机框架材料整体柱及其在富集和电色谱分离中的应用(21765002), 2018.1~2021.12, 主持(已结题);

4. 国家自然科学基金:基于金属-有机骨架材料的磁性纳米粒子和整体柱的制备及用于多环芳烃电色谱分析研究(21365005),2014.1~2017.12, 主持(已结题);

5. 国家自然科学基金:在线亲和预富集芯片手性整体柱电色谱技术用于生物体内及单细胞中手性物质的分析研究(21065002), 2011.1~2013.12, 主持(已结题);

6. 广西自然科学基金重点项目:基于MOF纳米酶的荧光传感平台构建及其用于有机磷农药残留分析(2017GXNSFDA198044), 2017.9~2021.9, 主持(已结题);

7.广西自然科学基金联合资助培育项目:单原子合金纳米酶的设计合成及肿瘤化学动力学疗法研究(2019GXNSFAA245014),2020.1~2022.1 主持(已结题);

8. 广西自然科学杰出青年基金:基于功能化MOFs膜涂层的磁性纳米粒子和电色谱整体柱的制备及其应用研究(2014GXNSFGA118002), 2014.6~2017.5,主持(已结题);

9.广西自然科学基金面上项目:MOFs聚合物毛细管固相微萃取整体柱的制备及其应用研究(2012GXNSFAA053024),2012.1~2014.12主持(已结题);

10.广西自然科学基金应用基础专项:新型硅胶基质毛细管整体柱的制备及应用研究(0731004),2007.5~2010.4, 主持(已结题);

获奖情况

1. 2022年广西自然科学奖一等奖(第一完成人)

2. 2014年广西自然科学奖一等奖(第四完成人)

3. 2010年广西自然科学奖二等奖(第二完成人)

4. 2014年广西自然科学杰出青年基金获得者

5. 2013年入选广西师范大学拔尖人才