文长春 博士，正高级实验师/副研究员

联系方式: 18977326616

E-mail: wcchun@163.com

基本介绍:

文长春，男，汉族，四川广安人，理学博士，正高级实验师/副研究员，硕士生导师。主要研究兴趣：诊疗纳米材料、纳米中药的合成及应用研究、生物无机化学、显微拉曼光谱等。曾获得广西师范大学“先进工作者” “评建创优先进个人”等荣誉。

近年发表论文与授权专利：

23. Bingbing Cai¹, Jian Liu¹, Qi Fang, Yuzhu Zhou, Sana Zahoor, Xiaohuan Guo*, Changchun Wen*, Au@CuS@CuO₂ nanoconstructs self-generate H₂O₂ and GSH-consuming enhanced CDT combined with PTT for cancer therapy, Journal of Photochemistry and Photobiology A: Chemistry 2026, 472, 116758.

22. Sana Zahoor¹, Sheraz Muhammad¹, Muhammad Kashif, Natasha Shahzad, Yan-cheng Liu, Cumali Celik, Nida Ambreen, AsifAli, Hui-Fen Wu*, Shohreh Azizi*, Changchun Wen*, Advances in mesoporous nanomaterials for photocatalytic degradation of pollutants: fundamentals,material classifications, challenges and future prospects, Coordination Chemistry Reviews 2026, 549, 217239.

21. Qi Fang¹, Chongwen Luo¹, Xiaohuan Guo, Bingbing Cai,Yuzhu Zhou, Kun Hu*, Changchun Wen*, Tumor microenvironment-activated core–shell structure Cu-Q@Co/ZIF-8 for chemotherapy/chemodynamic therapy of cancer, Journal of Materials Science 2025, 60(45), 22865-22879.

20. Xiaohuan Guo¹, Bingbing Cai¹, Qi Fang, Yanyan Chen, YuzhuZhou, Zhixing Liang, Changchun Wen*, Yan-Cheng Liu*, Hong Liang*, Norcantharidin/Cu²⁺dual-depleting GSH nanocatalyst with pH-responsive for CT/CDT synergisticcancer therapy, Materials Today Bio 2025, 33, 101959.

19. Minzhe Li¹, Yuzhu Zhou¹, Guimei Wei, Wenyi Wang, ZhixingLiang, Changchun Wen*, Xiang-Cheng Lin*, An environmental governance-oriented nanoplatform for persistent ultrasensitive SERS detection and photocatalytic elimination of organic dyes in water, Microchimica Acta 2025, 192(11), 722.

18. Xiang-Cheng Lin*^,1, Miaomiao Hu¹, Minzhe Li, Jian Liu, QinjieKou, Rong Huang, Lixian Sun, Changchun Wen*, Construction ofmagnetic Au/Fe₃O₄/POPs substrate with high enrichment capacity for SERS detection of gastric cancer marker 4-hydroxybenzoic acid,Microchemical Journal 2025, 113386.

17. Xiang-Cheng Lin*, Jian Liu, Miaomiao Hu, Lingjun Song, Minzhe Li,Qinjie Kou, Rong Huang, Lixian Sun, Changchun Wen*, An Au@CuS@CuO₂ nanoplatform with peroxidase mimetic activity and self-supply H₂O₂ properties for SERS detection of GSH, Spectrochimica Acta Part A: Molecular andBiomolecular Spectroscopy 2025, 340, 126376.

16. Minzhe Li, Guimei Wei, Zhixing Liang, Wenyi Wang, Changchun Wen*, Lixian Sun, Xiang-Cheng Lin*, Porous boron nitride–coupled gold nanorods enable highly sensitive SERS detection of tetracycline hydrochloride, Microchimica Acta 2025, 192(8),466.

15. Minzhe Li, Guimei Wei, Zhixing Liang, Wenyi Wang, Changchun Wen*, Lixian Sun, Xiang-Cheng Lin*, In situ growth of gold nanoparticles onnickel-aluminum layered double hydroxide for dye SERS detection andphotocatalytic degradation, Colloids and Surfaces A: Physicochemical and Engineering Aspects 2025, 713, 136537.

14. Miaomiao Hu, Changchun Wen*, Jian Liu, Minzhe Li, Nan Leng, Xiaohuan Guo, Qi Fang, Qinjie Kou, Rong Huang, Xiang-Cheng Lin*. Ratiometric Surface-enhanced Raman spectroscopy detection of 5-hydroxyindole-3-acetic acid based on Au@MIL-125@MIPs substrates, Talanta 2024, 281, 126880.

13. Nan Leng¹, Yuzhu Zhou¹, Changchun Wen*, Qi Fang, Xiaohuan Guo, Bingbing Cai, Ke-Bin Huang, Hong Liang*. GSH responsive AuNRs@TFF nanotheranostic for NIR-II photoacoustic imaging-guided CDT/PTT synergistic cancer therapy, Biomaterials Advances 2024, 166,14056.

12. Huihui Liu, Cunji Gao*, Peijing Xu, Yingshu Li, Xiaoxiao Yan, Xiaolu Guo, Changchun Wen*, Xing-Can Shen*. Biomimetic Gold Nanorods-Manganese Porphyrinswith Surface-Enhanced Raman Scattering Effect for Photoacoustic Imaging-Guided Photothermal/PhotodynamicTherapy, Small 2024, 2401117.

11. Xiaohuan Guo, Qi Fang, Nan Leng, Yuan Liu, Bingbing Cai, Yuzhu Zhou, Changchun Wen*. Hyaluronicacid modified Cu/Mn-doped metal-organic framework nanocatalyst for chemodynamictherapy, Biomedical Materials 2024, 19, 065025.

10. Peijing Xu¹, Changchun Wen¹, Cunji Gao*, Huihui Liu, Yingshu Li, Xiaolu Guo, Xing-Can Shen*,Hong Liang*, Near-Infrared-II-Activatable Self-Assembled Manganese Porphyrin-Gold Heterostructures for Photoacoustic Imaging-Guided Sonodynamic-Augmented Photothermal/Photodynamic Therapy. ACS Nano 2024, 18 (1),713-727.

9. Jian Liu, Changchun Wen*, Miaomiao Hu, Nan Leng, Xiang-Cheng Lin*, Mechanism underlying theeffect of MnO2 nanosheets for A549 cell chemodynamic therapy. Microchimica Acta 2023, 190 (10), 381.

8. Miaomiao Hu, Changchun Wen*, Jian Liu, Ping Cai, Nianqi Meng, Xue Qin, Peijing Xu, Zhilang Li, Xiang-Cheng Lin*, Mechanism of Cytotoxic Action of Gold Nanorods PhotothermalTherapy for A549 Cell. ACS Applied Bio Materials 2023, 6,1886−1895.

7. Jian Liu, Changchun Wen*, Miaomiao Hu, Juan Long, Jing Zhang, Minzhe Li, Xiang-Cheng Lin*, Metabolomics analysis of MnO2 nanosheets CDT for breast cancer cellsand mechanism of cytotoxic action. RSC Advances 2023, 13 (38),26630-26639.

6. Jing Zhang, Miaomiao Hu, Changchun Wen*, Jiang Liu, Fang Yu, Juan Long, Xiang-Cheng Lin*, CeO2@CuS@PDA-FA as targeted near-infrared PTT/CDT therapeutic agentsfor cancer cells. Biomedical Materials 2023, 18 (6), 065006.

5. Changchun Wen¹, Xiaolu Guo¹, Cunji Gao, Zhongkai Zhu, Nianqi Meng, Xing-Can Shen, Hong Liang*, NIR-II-responsiveAuNRs@SiO2-RB@MnO2 nanotheranostic for multimodalimaging-guided CDT/PTT synergistic cancer therapy. Journal of Materials Chemistry B 2022, 10, 4274–4284.

4. Changchun Wen, Liping Wang, Li Liu, Xing-Can Shen, Hua Chen*, Surface-enhanced Raman probes based ongold nanomaterials for in vivo diagnosis and imaging. Chemistry - An Asian Journal 2022,e202200014.

3. Xiaolu Guo¹, Changchun Wen¹, Qianxin Xu, Changping Ruan, Xing-Can Shen*, Hong Liang*, A full-spectrum responsive B-TiO2@SiO2-HA nanotheranostic system for NIR-II photoacoustic imaging-guided cancerphototherapy. Journalof Materials Chemistry B 2021, 9,2042-2053.

2. Changchun Wen, Hua Chen*, Xiaolu Guo, Zhaoxing Lin, ShupingZhang, Xing-Can Shen, Hong Liang*, Lysosome-Targeted gold nanotheranosticsfor in situ SERS monitoring pH and multimodal imaging-guided phototherapy. Langmuir 2021, 37: 569-577.

1. 文长春, 张亮亮, 韦春芳, 纪仕辰, 沈星灿*, 梁宏*. 无机纳米-生物界面作用的SERS研究. 中国科学: 化学[J], 2017, 47(2), 183-190.

1. 拉曼光谱检测液体样品池；专利号：201920655690.2；中华人民共和国国家知识产权局。

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