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基本介绍

博士，教授。2012年6月毕业于中南大学，获工学博士学位。2012年7月到广西师范大学工作，2013年晋升副教授。2017年破格晋升教授。2016年入选广西师范大学拔尖人才计划，2017年入选广西高等学校千名中青年骨干教师培育计划人选，2018年被评为广西师范大学优秀教师，2019年入选广西“十百千”人才工程第二层次人选，广西青年特聘专家，2019-2020年到美国Stanford University作访问研究。先后主持国家自然科学基金3项、广西自然科学基金项目2项，参与国家自然科学基金及省部级科研项目多项。迄今，已在Anal. Chem., Chem. Commun., Biosen. Bioelectron., Chem. Eur. J., Sensor Actuat. B-Chem., J. Chromatogr. A, Microchim. Acta, Anal. Chim. Acta等国外学术期刊上发表SCI收录论文80余篇。曾获2018年度广西科学技术奖（自然科学类）一等奖（第一完成人）、2014年度广西科学技术奖（自然科学类）一等奖（第三完成人）、第十四届广西青年科技奖（2017年）、广西自然科学优秀论文二等奖2项（2011年、2012年）。曾任中国青年科技工作者协会第六届理事会理事、Front. Chem.客座编委，现为ACS Nano, Small, Theranostics, Nanoscale, Anal. Chem., Chem. Commun., Biosen. Bioelectron., Expert Opin. Drug. Del., Sensor Actuat. B-Chem., Microchim. Acta, Anal. Chim. Acta等20余种期刊审稿人。

研究方向

生物传感器、药物筛选及载药系统研究

代表性论文

1.  Jiayao Xu, Lina Fang, Ming Shi, Yong Huang,* Lifang Yao, Shulin Zhao,* Liangliang Zhang, Hong Liang,* A peptide-based four-color fluorescent polydopamine nanoprobe for multiplexed sensing and imaging of proteases in living cells.  Chemical communications, 2019, 55(11): 1651-1654.

2. Lifang Yao, Jiayao Xu, Ming Shi, Yong Huang,* Lina Fang, Shulin Zhao,* Zhen-Feng Chen, HongLiang,* Polydopamine nanoparticle-based multicolor proximity immunoassays for ultrasensitive, multiplexed analysis of proteins using isothermal quadratic amplification.  Sensors and Actuators B: Chemical, 2019, 282: 626-635.

3. Jiayao Xu, Ming Shi, Wenting Chen, Yong Huang,* Lina Fang, Lifang Yao, Shulin Zhao,* Zhen-Feng Chen, Hong Liang,* A gold nanoparticle-based four-color proximity immunoassay for one-step, multiplexed detection of protein biomarkers using ribonuclease H signal amplification. Chemical Communications, 2018, 54, 2719-2722.

4. Yong Huang,* Huakui Huang, Jian Qin, Xiaoqian Liu, Shulin Zhao,* Zhen-Feng Chen, Hong Liang,* A graphene oxide-based multiplexed fluorescence assay for the detection of protein kinase activity in cell lysates and the evaluation of protein kinase inhibition. Sensors and Actuators B: Chemical, 2017, 238, 908-916.

5. Yong Huang,* Xiaoqian Liu, Huakui Huang, Jian Qin, Liangliang Zhang, Shulin Zhao,* Zhen-Feng Chen, Hong Liang,* Attomolar detection of proteins via cascade strand-displacement amplification and polystyrene nanoparticle enhancement in fluorescence polarization aptasensors. Analytical Chemistry, 2015, 87, 8107-8114

6. Yong Huang,* Xiaoqian Liu, Liangliang Zhang Kun Hu, Shulin Zhao,* Baizong Fang, Zhen-Feng Chen, Hong Liang,* Nicking enzyme and graphene oxide-based dual signal amplification for ultrasensitive aptamer-based fluorescence polarization assay.  Biosensors and Bioelectronics, 2015, 63, 178-184.

7. Yong Huang, Ming Shi, Limin Zhao, Shulin Zhao*, Kun Hu, Zheng-Feng Chen, Jia Chen, Hong Liang,* Carbon nanotube signal amplification for ultrasensitive fluorescence polarization detection of DNA methyltransferase activity and inhibition. Biosensors and Bioelectronics, 2014, 54, 285-291.

8. Yong Huang, Shulin Zhao,* Zhen-Feng Chen, Ming Shi, Hong Liang,* Amplified fluorescence polarization aptasensors based on structure-switching-triggered nanoparticles enhancement for bioassays. Chemical Communications, 2012, 48,7480-7482.

9. Yong Huang, Shulin Zhao,* Zhen-Feng Chen, Ming Shi, Jia Chen, Hong Liang,* An amplified chemiluminescence aptasensor based on bi-resonance energy transfer ongold nanoparticles and exonuclease III-catalyzed target recycling. Chemical Communications, 2012, 48,11877-11879.

10. Yong Huang, Shulin Zhao,* Yi-Ming Liu, Jia Chen, Zhen-Feng Chen, Ming Shi, Hong Liang,* An amplified single-walled carbon nanotube-mediated chemiluminescence turn-on sensing platform for ultrasensitive DNA detection. Chemical Communications, 2012, 48,9400-9402.

11. Yong Huang, Shulin Zhao,* Zhen-Feng Chen, Yan-Cheng Liu, Hong Liang,* Ultrasensitive endonuclease activity and inhibition detection using gold nanoparticle-enhanced fluorescence polarization. Chemical Communications, 2011, 47,4763-476;

12. Yong Huang, Shulin Zhao,* Ming Shi, Jia Chen, Zhen-Feng Chen, Hong Liang,* Intermolecular and intramolecular quencher based quantum dot nanoprobes for multiplexed detection of endonuclease activity and inhibition. Analytical chemistry, 2011, 83, 8913-8918.