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博士，研究员，硕士/博士研究生导师，德国尤斯图斯-李比希-吉森大学/德国弗劳恩霍夫分子生物学和应用生态研究所（吉森）访问学者。长期从事广西特色药用植物共附生微生物、海洋微生物代谢产物中有效成分的提取、分离及活性研究。先后主持国家自然科学基金、广西自然科学基金、药用资源化学与药物分子工程教育部重点实验室主任基金、广西医药产业人才小高地基金、桂林市科技研发项目等各级科研项目的研究工作；参与科技部973前期研究专项、863计划、国家自然基金、广西重点基金等项目的研究工作。在国内外学术刊物上发表论文五十余篇，获国家发明专利授权2项，参与编著《化学实验竞赛指导（第二版）》、《海洋生物活性化合物手册》。

广西特色药用植物及共附生微生物中活性成分提取、分离及结构修饰，生物有机与药物化学相关领域的研究

（课题组招收有机化学、生物与医药等专业研究生，有意者可通过邮件联系）

2003/09 - 2006/07，中山大学，化学与化学工程学院，有机化学专业，博士

2000/09 - 2003/07，广西师范大学，化学化工学院，有机化学专业，硕士

1996/09 - 2000/07，广西师范大学，化学化工学院，学士 

本科生《有机化学》、《有机化学实验》；研究生《有机化学前沿》

1. Tu-Xiang Mo#, Xi-Shan Huang #, Wen-Xiu Zhang, Till F. Schӓberle, Jiang-Ke Qin, De-Xiong Zhou, Xiao-Ya Qin, Zhao-Long Xu, Jun Li, Rui-Yun Yang*. A Series of Meroterpenoids with Rearranged Skeletons from an Endophytic Fungus Penicillium sp. GDGJ-285. Organic Chemistry Frontiers, 2021, 8, 2232-2241.

2. Xiaoya Qin, Jiguo Huang, Dexiong Zhou, Wenxiu Zhang, Yanjun Zhang, Jun Li, Ruiyun Yang*, Xishan Huang*. Polyketide Derivatives, Guhypoxylonols A–D from a Mangrove Endophytic Fungus Aspergillus sp. GXNU-Y45 That Inhibit Nitric Oxide Production. Marine Drugs, 2022, 20, 5.

3. Yu-Yue Qin#, Xi-Shan Huang#, Xiao-Bo Liu, Tu-Xiang Mo, Zhao-Long Xu, Ben-Chao Li, Xiao-Ya Qin, Jun Li , Till F. Schӓberle, Rui-Yun Yang*. Three new andrastin derivatives from the endophytic fungus Penicillium vulpinum. Natural Product Research, 2022,36(13),3262-3670.

4. Yuyue Qin#, Xiaobo Liu#, Jing Lin, Jingying Huang, Xiaofei Jiang, Tuxiang Mo, Zhaolong Xu, Jun Li, Ruiyun Yang*. Two new phthalide derivatives from the endophytic fungus Penicillium vulpinum isolated from Sophora tonkinensis. Natural Product Research, 2021, 35(3), 421-427.

5. Xishan Huang#, Dexiong Zhou#, Yan Liang, Xiaobo Liu, Fei Cao, Yuyue Qin, Tuxiang Mo, Zhaolong Xu, Jun Li*, Ruiyun Yang*. Cytochalasins from endophytic Diaporthe sp. GDG-118. Natural Product Research, 2021, 35(20), 3396-3403.

6. Zhao-Long Xu, Shi-Man Cao, Yu-Yue Qin, Tu-Xiang Mo, Ben-Chao Li, Xiao-Ya Qin, Xi-Shan Huang, Jun Li, Rui-Yun Yang*. Chemical constituents of the endophytic fungus Penicillium macrosclerotiorum from Sophora tonkinensis. Chemistry of Natural Compounds, 2021, 57(3), 542-544.

7. Tu-Xiang Mo, Xiao-Bo Liu, Long-Hui Duan, Xue-Mei Zhang, Zhao-Long Xu, Xiao-Ya Qin, Ben-Chao Li, Jun Li, Rui-Yun Yang*. Secondary Metabolites of the Endophytic Fungus Xylaria sp. GDG-102 from Sophora tonkinensis. Chemistry of Natural Compounds, 2021, 57(4), 764-766.

8. Zhao-Long Xu, Na Zheng, Shi-man Cao, Shi-Ting Li, Tu-Xiang Mo, Yu-Yue Qin, Jun Li, Rui-Yun Yang*. Secondary metabolites from the endophytic fungus Stemphylium lycopersici and their antibacterial activities. Chemistry of Natural Compounds, 2020, 56(6), 1162-11675.

9. Yan Liang, Weifeng Xu, Chengmei Liu, Dexiong Zhou, Xiaobo Liu, Yuyue Qin, Fei Cao, Jun Li, Ruiyun Yang*, Jiangke Qin*. Eremophilane sesquiterpenes from the endophytic fungus Xylaria sp. GDG-102. Natural product research, 2019, 33(9), 1304-1309.

10. Xiao-Bo Liu, Na Zheng, Li-Qi Liang, Dong-Min Zhao, Yu-Yue Qin, Jun Li, Rui-Yun Yang*. Secondary metabolites from the endophytic fungus Fusarium equiseti and their antibacterial activities. Chemistry of Natural Compounds, 2019, 55(6), 1141-1144.

11. Na Zheng, Feihua Yao, Xuefeng Liang, Quan Liu, Weifeng Xu, Yan Liang, Xiaobo Liu, Jun Li, Ruiyun Yang*. A new phthalide from the endophytic fungus Xylaria sp. GDG-102. Natural product research,2018,32(7), 755-760.

12. Na Zheng, Quan Liu,Dong-Lan He, Yan Liang, Jun Li, Rui-Yun Yang*. A new compound from the endophytic fungus Xylaria sp. from Sophora tonkinensis. Chemistry of natural compounds, 2018,54(3), 447-449.

13. De-Xiong Zhou, Yan Liang, Xiao-Bo Liu, Na Zheng, Wei-feng Xu, Jun Li, Rui-Yun Yang*. APORPHINE ALKALOIDS FROM Stephania dielsiana.Chemistry of natural compounds, 2018,54(6), 1202-1204.

14. Wei-Feng Xu, Xue-Mei Hou,Fei-Hua Yao,Na Zheng,Jun Li,Chang-Yun Wang, Rui-Yun Yang*, Chang-Lun Shao*. Xylapeptide A, an Antibacterial Cyclopentapeptide with an Uncommon L-Pipecolinic Acid Moiety from the associated Fungus Xylaria sp. (GDG-102). Scientific reports, 2017, 7, DOI:10.1038/s41598-017-07331-4. 

15. Weifeng Xu, Xuemei Hou, Kailin Yang, Fei Cao, Ruiyun Yang*, Changyun Wang, Changlun Shao*. Nigrodiquinone A, a Hydroanthraquinone Dimer Containing a Rare C-9–C-71 Linkage from a Zoanthid-Derived Nigrospora sp. Fungus [J]. Marine Drugs, 2016, 14, 51, doi: 10.3390/md14030051.

16. Rui-Yun Yang*, Xin-Zhu Wang, Bo Wei, De-Xiong Zhou, Wei-feng Xu, Hong Liang, Zhen-Feng Chen, Jun Li. Chemical constituents from the stems of Flemingia strobilifera (Linn.) Ait.  Chemistry of Natural Compounds, 2016, 52(1), 122-123.

17. Ruiyun Yang, Xilin Ouyang, Dianhua Gan, Hengshan Wang, Yizheng Li, Yingming Pan. Isolation and Determination of Iridoid Glycosides From the Seeds of Osmanthusfragrans by HPLC. Analytical Letters, Analytical Letters, 2013, 46, 745-752.

18. RuiYun Yang*, YanSu Lan, ZhongJing Huang, ChangLun Shao, Hong Liang*, ZhengFeng Chen, Li Jun. A new isoflavonol glycoside from the roots of Sophora tonkinensis. Records of Natural Products, 2012, 6(3), 212-217.

19. RuiYun Yang*, YanSu Lan, ZhongJing Huang, ChangLun Shao, Hong Liang*, ZhengFeng Chen, Li Jun. Isoflavonoids from Sophora tonkinensis. Chemistry of Natural Compounds, 2012, 48(4), 674-676.
    

国家自然科学基金，21762007，广豆根内生真菌中抗菌活性代谢产物的发现及相关作用机制研究。

广西自然科学基金面上项目，2023GXNSFAA026228，基于单菌多产物策略的3株山豆根内生真菌中抗菌活性成分发现的应用基础研究。

广西自然科学基金面上项目，2014GXNSFAA118055，中药血散薯中抗菌活性成分研究。

省部共建药用资源化学与药物分子工程国家重点实验室开放基金项目，CMEMR2016-A06，广豆根内生真菌中抗菌活性代谢产物研究。

桂林市科学研究与技术开发计划项目，2016010301-2，广西特色中药材血散薯抗菌成分的分离及提取工艺研究。

广西医药产业人才小高地项目，1310，广西血散薯化学成分和药理活性研究。