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Academic Achievement

1．Pei Liu, Heng-shan Wang, Ying-ming Pan,* Wei-long Dai, Hong Liang and Zhen-Feng Chen*. The first palladium-catalyzed 1,4-addition of terminal alkenes to acrylate esters. Chem. Commoun., 2013, 49, 5295-5297.

2. Yan-Cheng Liu, Zhen-Feng Chen*, Xiao-Yan Song, Yan Peng, Qi-Pin Qin, Hong Liang*. Synthesis, crystal structure, cytotoxicity and DNA interaction of 5,7-dibromo-8-quinolinolato- lanthanides. European Journal of Medicinal Chemistry, 2013, 59, 168-175.

3. Zhen-Feng Chen*, Yun-Qiong Gu, Xiao-Yan Song, Yan-Cheng Liu, Yan Peng, Hong Liang*. Synthesis, crystal structure, cytotoxicity and DNA interaction of 5,7-dichloro-8- quinolinolato-lanthanides. European Journal of Medicinal Chemistry, 2013, 59, 194-202.

4. Zhen-Feng Chen*, Yan Peng, Yun-Qiong Gu, Yan-Cheng Liu, Mei Liu, Ke-Bin Huang, Kun Hu and Hong Liang*. High antitumor activity of 5,7-dihalo-8- quinolinolato tin(IV) complexes. European Journal of Medicinal Chemistry, 2013, 2013, 62,51-58.

5. Ke-Bin Huang, Zhen-Feng Chen*, Yan-Cheng Liu, Zhu-Quan Li, Jian-Hua Wei, Meng Wang， Guo-Hai Zhang, Hong Liang*. Platinum(II) complexes with mono-aminopho- sphonate ester targeting group that induce apoptosis through G1 cell-cycle arrest: Synthesis, crystal structure and antitumour activity. European Journal of Medicinal Chemistry, 2013, 63, 76-84.

6. Ke-Bin Huang, Zhen-Feng Chen,* Yan-Cheng Liu, Zhu-Quan Li, Jian-Hua Wei, Meng Wang, Xiao-Li Xie, and Hong Liang*. Platinum(II) complexes containing aminophosphonate esters: synthsis, characterization, cytotoxicity and action mechanism. European Journal of Medicinal Chemistry, 2013, 64,554-561.

7. Yan Peng, Min-Min Zhang, Zhen-Feng Chen,* Kun Hu, Yan-Cheng Liu, Xia Chen and Hong Liang*. Synthesis, characterization and interaction with biomolecules of platinum(II) complexes with shikimic acid-based ligands. Bioinorganic Chemistry and Applications, Volume 2013, Article ID 565032, 12 pages.

8．Zhen-Feng Chen*, Yan-Fang Shi, Yan-Cheng Liu, Xue Hong, Bo Geng, Yan Peng, Hong Liang*, TCM active ingredient oxoglaucine metal complexes: Crystal structure, cytotoxicity and interaction with DNA. Inorganic Chemistry, 2012, 51, 1998-2009.

9．Huang Tang, Hai-Tao Zhao, Shu-Ming Zhong, Zhi-Yu Wang, Zhen-Fen Chen*, Hong Liang*, Novel oxoisoaporphine-based inhibitors of acetyl- and butyrylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation. Bioorganic & Medicinal Chemistry Letters, 2012, 22, 2257-2261.

10．Zhen-Feng Chen*, Yan-Cheng Liu, Yan Peng, Xue Hong, Hong-Hong Wang, Min-Min Zhang, Hong Liang. Synthesis, characterization, and in vitro antitumor properties of gold(III) compounds with the traditional Chinese medicine (TCM) active ingredient liriodenine. J. Biol. Inorg. Chem., 2012, 17(2), 247-261.

11．Zhen-Feng Chen*, Li Mao, Li-Min Liu, Yan-Cheng Liu,Yan Peng, Xue Hong, Hong-Hong Wang, Hua-Gang Liu, Hong Liang*. Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) matrine with Ga(III), Au(III), Sn(IV) ions, and DNA binding studies. J. Inorg. Biochem., 2011, 105, 171-180.

12．Zhen-Feng Chen*, Xiao-Yan Song, Yan Peng, Xue Hong, Yan-Cheng Liu, Hong Liang. High cytotoxicity of dihalo-substituted 8-quinolinolato-lanthanides. Dalton Trans., 2011, 40，1684-1692.

13． Zhen-Feng Chen*, Ming-Xiong Tan, Yan-Cheng Liu, Yan Peng, Hong-Hong Wang, Hua-Gang Liu and Hong Liang*. Synthesis, Characterization and Preliminary Cytotoxicity Evaluation of Five Lanthanide(III)-Plumbagin Complexes. J. Inorg. Biochem., 2011, 105，308-316.

14. Huang Tang, Li-Zhen Zhao, Hao-Tao Zhao, Shi-Liang Huang, Shu-Ming Zhong, Jiang-Ke Qin, Zhen-Feng Chen,* Zhi-Shu Huang, Hong Liang. Hybrids of oxoisoaporphine-tacrine congeners: Novel acetylcholinesterase and acetylcholinesterase- induced b-amyloid aggregation inhibitors. European Journal of Medicinal Chemistry, 2011, 46, 4970-4979.

15. Zhen-Feng Chen*, Hong Liang*, Progresses in TCM Metal-Based Antitumour Agents, Anti-Cancer Agents in Medicinal Chemistry, 2010, 10, 412-423.

16. Zhen-Feng Chen*, Yan-Cheng Liu, Li-Min Liu, Heng-Shan Wang, San-Hai Qin, Bo-Long Wang, He-Dong Bian, Bin Yang, Hoong-Kun Fun, Hua-Gang Liu, Hong Lian and Chris Orvig, Potential new inorganic antitumour agents from combining the anticancer traditional Chinese medicine (TCM) liriodenine with metal ions, and DNA binding studies, Dalton Trans.,2009,(2): 262-272.

17．Yan-Cheng Liu, Zhen-Feng Chen*, Li-Min Liu, Yan Peng, Xue Hong, Bin Yang,Hua-Gang Liu,Hong Liang and Chris Orvig, Divalent later transition metal complexes of the traditional chinese medicine (TCM) liriodenine: coordination chemistry, cytotoxicity and DNA binding studies, Dalton Trans., 2009, (48): 10813-10823.

18．Zhen-Feng Chen*, Ming-Xiong Tan, Li-Min Liu, Yan-Cheng Liu, Heng-Shan Wang,Bin Yang,Yan Peng, Hua-Gang Liu, Hong Liang and Chris Orvig, Cytotoxicity of the traditional chinese medicine (TCM) plumbagin in its copper chemistry, Dalton Trans.,2009, (48):10824-10833.

19．Meryn L. Bowen, Zhen-Feng Chen, Adrienne M. Roos, Ripen Misri, Urs Hafeli, Michael J. Adam and Chris Orvig, Long-chain rhenium and technetium glucosamine conjugates, Dalton Trans., 2009, 9228-9236.

20．Zhen-Feng Chen*, Shu-Feng Zhang, Hai-Sheng Luo, Brendan F. Abrahams and Hong Liang. Ni2(R*COO)4(4,4’-bipy)2----a robust homochrial quartz-like network with large chiral channels. CrystEngComm, 2007, 9, 7-29.

21. Zhen-Feng Chen*, Zhi-Li Zhang,Yu-Hui Tan,Yun-Zhi Tang,Hoong-Kun Fun, Zhong-Yuan Zhou, Brendan F. Abrahams and Hong Liang. Coordination polymers constructed by linking metal ions with azodibenzoate anions. CrystEngComm, 2008, 10, 17-231.

22. Zhi-Rong Qu, Zhen-Feng Chen*, et al. The first highly stable homochiral olefin-copper(I) 2D coordination polymer grid based on quinine as a building block.Organometallics, 2003，22，2814-2816.

23. Zhen-Feng Chen, Ren-Gen Xiong, Jing Zhang, Xue-Tai Chen, Zi-Ling Xue, Xiao-Zeng You. 2D molecular square grid with strong blue fluorescent emission: a complex of norfloxacin with Zinc(II). Inorganic Chemistry，2001，40(16)，4075-4077.

24. Zhen-Feng Chen, Ren-Gen Xiong, Abrahams Brendan F., Xiao-Zeng You, Chi-Ming Che. An unprecedented six-fold anion-type chiral diamondoid-like eight-coordinate Cd(II) coordination polymer with a second-order nonlinear optical effect. Dalton Trans, 2001，(17),2453-2455.